GTPBP3

Across TCGA pan-cancer cohorts, GTPBP3 RNA differs between tumor and matched normal tissue in 15 of 18 cancer types tested, making tumor–normal expression one of GTPBP3’s most consistent transcriptional readouts.

The strongest signal is observed in colon adenocarcinoma (COAD), where GTPBP3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GTPBP3 is over-expressed in tumor.

COAD, BLCA, and KIRP are the cancer types where GTPBP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GTPBP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
COAD	Male	IV	+1.442	<.001	11	view →
BLCA	Male	All	+1.395	<.001	11	view →
KIRP	All	II,III,IV	+0.915	<.001	11	view →
HNSC	Male	III,IV	+0.897	<.001	11	view →
KIRC	Male	IV	+0.575	<.001	11	view →
LIHC	Female	II,III,IV	+1.079	<.001	9	view →
LUAD	All	III,IV	+0.816	<.001	9	view →
LUSC	Male	III,IV	+1.612	<.001	8	view →
STAD	Male	II,III,IV	+1.081	<.001	8	view →
BRCA	All	II,III,IV	+0.573	<.001	6	view →
UCEC	All	All	+0.548	<.001	6	view →
CHOL	Female	All	+2.110	<.001	5	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 15 lineages.

GTPBP3–COAD

Open the COAD breakdown →