GTF3A

Across TCGA cell cohorts, GTF3A RNA expression is significantly associated with the go_rna of many other GO terms, with 3,336 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GTF3A-associated GO terms across cancer lineages are Sister chromatid biorientation, Cajal body organization, and Establishment of meiotic spindle orientation. Each is linked with GTF3A in more than 11 cancer types. Because this analysis shows association rather than direction, both GTF3A-to-partner and partner-to-GTF3A results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Sister chromatid biorientation grouped by GTF3A-low versus GTF3A-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF3A→partner) and Y-score (partner→GTF3A) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Sister chromatid biorientation →	+0.190	+0.975	<.001	.001	3	12
SOFT_TISSUE	Cajal body organization →	+0.123	+0.780	<.001	<.001	3	12
URINARY_TRACT	Establishment of meiotic spindle orientation →	+0.142	+1.090	.007	.001	3	12
OESOPHAGUS	Positive regulation of canonical NF-kappaB signal transduction →	-0.064	-1.060	.003	.002	3	11
UPPER_AERODIGESTIVE_TRACT	Pyrimidine nucleoside triphosphate catabolic process →	+0.145	+1.009	.002	.004	3	11
PANCREAS	Positive regulation of metaphase/anaphase transition of cell cycle →	+0.113	+0.820	<.001	.001	2	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,336 associations by consensus.

Sister chromatid biorientation by GTF3A expression — BONE

Explore this box plot interactively →