Across TCGA patient cohorts, GTF2H2C mutation is significantly associated with the RNA expression of many other genes, with 45 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GTF2H2C-associated genes across cancer lineages are MIR8053, RAB28P2, and NUTF2P8. Each is linked with GTF2H2C in more than 1 cancer types. Because this analysis shows association rather than direction, both GTF2H2C-to-partner and partner-to-GTF2H2C results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GTF2H2C→partner) and Y-score (partner→GTF2H2C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MIR8053 →	+0.389	+3.997	<.001	.009	3	2
UCEC	RAB28P2 →	+0.104	+4.137	<.001	.008	3	2
UCEC	NUTF2P8 →	+0.129	+3.246	.001	.008	3	1
UCEC	RN7SL248P →	+0.167	+4.985	<.001	<.001	3	1
UCEC	SMCP →	+0.222	+3.193	<.001	.004	3	1
UCEC	C5orf64 →	+0.127	+3.697	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 45 associations by consensus.

Exploration

GTF2H2C survival (RNA) · tumor vs normal (RNA) · all GTF2H2C data types