GSTM2P1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GSTM2P1 mutation is significantly associated with the RNA expression of many other genes, with 95 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible GSTM2P1-associated genes across cancer lineages are RNU4-58P, RN7SL248P, and DNAJB5P1. Each is linked with GSTM2P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GSTM2P1-to-partner and partner-to-GSTM2P1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTM2P1→partner) and Y-score (partner→GSTM2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCARNU4-58P →+0.355+5.106<.001.00832
UCECRN7SL248P →+0.279+6.307<.001<.00132
UCECDNAJB5P1 →+0.473+4.010<.001.00632
SKCMEZH2P1 →+0.146+3.145<.001.00432
BLCARPL36P20 →+0.175+5.329<.001.00632
BLCARN7SKP60 →+0.237+6.018<.001.00232
Each partner links to its Q-omics profile. Showing the 6 strongest of 95 associations by consensus.

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