GSTA5

Across TCGA patient cohorts, GSTA5 mutation is significantly associated with the RNA expression of many other genes, with 161 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GSTA5-associated genes across cancer lineages are OR6V1, RNU7-81P, and RN7SL554P. Each is linked with GSTA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both GSTA5-to-partner and partner-to-GSTA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR6V1 grouped by GSTA5-low versus GSTA5-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTA5→partner) and Y-score (partner→GSTA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	OR6V1 →	+0.058	+5.449	<.001	<.001	3	2
UCEC	RNU7-81P →	+0.271	+3.453	<.001	.003	3	2
BLCA	RN7SL554P →	+0.110	+4.685	.008	.007	3	2
SKCM	NEFHP1 →	+0.026	+2.725	<.001	.006	3	2
SKCM	SETP5 →	+0.153	+3.089	<.001	.003	3	1
SKCM	LINC01779 →	+0.122	+2.954	.002	.007	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 161 associations by consensus.

OR6V1 by GSTA5 expression — HNSC

Explore this box plot interactively →