GSTA5

Across TCGA pan-cancer cohorts, GSTA5 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of GSTA5’s most consistent transcriptional readouts.

The strongest signal is observed in stomach adenocarcinoma (STAD), where GSTA5 RNA is repressed in tumor relative to normal tissue. In most cancer types GSTA5 is over-expressed in tumor, although a few such as STAD and LUSC show the opposite, repressed pattern.

STAD, LUSC, and HNSC are the cancer types where GSTA5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GSTA5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
STAD	Male	All	−0.091	.014	5	view →
LUSC	All	All	−0.062	.007	5	view →
HNSC	All	All	−0.071	.031	4	view →
LUAD	Female	All	+0.145	<.001	2	view →
BRCA	All	III,IV	−0.096	.011	2	view →
KICH	All	II,III,IV	−0.047	.034	2	view →
THCA	All	All	+0.036	.024	2	view →
KIRP	Female	All	−0.056	.025	1	view →
CHOL	All	All	−0.052	.040	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

GSTA5–STAD

Open the STAD breakdown →