GSTA5

Across TCGA patient cohorts, GSTA5 mutation is significantly associated with the total protein of many other genes, with 9 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GSTA5-associated genes across cancer lineages are FASN, ACC1, and Ku80. Each is linked with GSTA5 in more than 1 cancer types. Because this analysis shows association rather than direction, both GSTA5-to-partner and partner-to-GSTA5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, FASN grouped by GSTA5-low versus GSTA5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTA5→partner) and Y-score (partner→GSTA5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FASN →	+0.588	+2.584	.001	.011	3	1
UCEC	ACC1 →	+0.663	+3.459	<.001	.005	3	1
UCEC	Ku80 →	+0.283	+1.887	.010	.031	3	1
UCEC	Rab11 →	-0.135	-2.302	.046	.034	3	1
UCEC	Rad50 →	-0.347	-2.584	.002	.011	3	1
UCEC	SCD →	+0.122	+2.331	.017	.019	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 9 associations by consensus.

FASN by GSTA5 expression — UCEC

Explore this box plot interactively →