GSTA3

Across TCGA patient cohorts, GSTA3 mutation is significantly associated with the total protein of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GSTA3-associated genes across cancer lineages are Annexin-1, TIGAR, and cIAP. Each is linked with GSTA3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GSTA3-to-partner and partner-to-GSTA3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Annexin-1 grouped by GSTA3-low versus GSTA3-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTA3→partner) and Y-score (partner→GSTA3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	Annexin-1 →	+0.980	+3.019	<.001	.019	3	1
UCEC	TIGAR →	+0.191	+3.196	.022	.010	1	1
UCEC	cIAP →	+0.183	+3.196	.015	.010	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

Annexin-1 by GSTA3 expression — UCEC

Explore this box plot interactively →