GSTA1

Across TCGA cell cohorts, GSTA1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible GSTA1-associated genes across cancer lineages are HOXB1, TAS2R7, and HELT. Each is linked with GSTA1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GSTA1-to-partner and partner-to-GSTA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, HOXB1 grouped by GSTA1-low versus GSTA1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSTA1→partner) and Y-score (partner→GSTA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	HOXB1 →	+0.019	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	TAS2R7 →	+0.032	+5.643	<.001	.002	3	1
BLOOD_Lymphoma	HELT →	+0.025	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	SIAH3 →	+0.062	+4.867	<.001	.009	3	1
BLOOD_Lymphoma	LYPD4 →	+0.118	+4.867	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

HOXB1 by GSTA1 expression — BLOOD_Lymphoma

Explore this box plot interactively →