GSTA1

Across TCGA pan-cancer cohorts, GSTA1 RNA differs between tumor and matched normal tissue in 13 of 18 cancer types tested, making tumor–normal expression one of GSTA1’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal papillary cell carcinoma (KIRP), where GSTA1 RNA is repressed in tumor relative to normal tissue. In most cancer types GSTA1 is over-expressed in tumor, although a few such as KIRP and KICH show the opposite, repressed pattern.

KIRP, KICH, and COAD are the cancer types where GSTA1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GSTA1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRP	Male	All	−4.895	<.001	11	view →
KICH	Male	II,III,IV	−6.448	<.001	10	view →
COAD	Female	II,III,IV	−2.708	<.001	9	view →
KIRC	All	II,III,IV	+1.973	<.001	7	view →
BRCA	All	III,IV	−2.904	<.001	6	view →
LUAD	Female	III,IV	−2.389	<.001	6	view →
HNSC	All	All	−1.889	.004	5	view →
LIHC	All	All	−1.219	.005	4	view →
THCA	All	All	+0.426	<.001	4	view →
CHOL	Female	All	−10.076	<.001	3	view →
READ	Female	All	−2.702	.001	2	view →
PRAD	All	All	−0.944	.015	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 13 lineages.

GSTA1–KIRP

Open the KIRP breakdown →