Across TCGA patient cohorts, GSPT2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,222 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible GSPT2-associated proteins across cancer lineages are FAM120C, CTPS2, and HCFC1. Each is linked with GSPT2 in more than 4 cancer types. Because this analysis shows association rather than direction, both GSPT2-to-partner and partner-to-GSPT2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GSPT2→partner) and Y-score (partner→GSPT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	FAM120C →	+0.363	+1.002	.004	.001	3	5
COAD	CTPS2 →	+0.331	+1.001	.005	.001	3	4
GBM	HCFC1 →	+0.207	+0.335	<.001	.001	3	4
HNSC	HNRNPA3 →	+0.271	+0.783	<.001	<.001	3	4
GBM	ATRX →	+0.290	+0.291	<.001	<.001	3	4
HNSC	ABI2_S227 →	+0.688	+0.975	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,222 associations by consensus.

Exploration

GSPT2 survival (RNA) · tumor vs normal (RNA) · all GSPT2 data types