GSG1L

Across TCGA patient cohorts, GSG1L protein abundance is significantly associated with the RNA expression of many other genes, with 896 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GSG1L-associated genes across cancer lineages are PNPLA5, CHGA, and ARHGAP5. Each is linked with GSG1L in more than 1 cancer types. Because this analysis shows association rather than direction, both GSG1L-to-partner and partner-to-GSG1L results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GSG1L versus PNPLA5 in GBM, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSG1L→partner) and Y-score (partner→GSG1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	PNPLA5 →	+0.375	+1.328	<.001	.001	3	1
GBM	CHGA →	+2.960	+1.345	.002	.002	3	1
GBM	ARHGAP5 →	+1.235	+1.518	.002	<.001	3	1
GBM	HRH3 →	+1.081	+1.013	.005	.004	3	1
GBM	CELF4 →	+2.554	+1.622	<.001	<.001	3	1
GBM	SYP →	+3.193	+1.730	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 896 associations by consensus.

GSG1L vs PNPLA5 — GBM

Explore this scatter interactively →