GSG1L

Across TCGA cell cohorts, GSG1L mutation is significantly associated with the RNA expression of many other genes, with 8 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GSG1L-associated genes across cancer lineages are OR5V1, OR2B3, and SEPTIN14. Each is linked with GSG1L in more than 1 cancer types. Because this analysis shows association rather than direction, both GSG1L-to-partner and partner-to-GSG1L results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR5V1 grouped by GSG1L-low versus GSG1L-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GSG1L→partner) and Y-score (partner→GSG1L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	OR5V1 →	+0.008	+4.437	<.001	.004	3	2
BREAST	OR2B3 →	+0.020	+5.781	<.001	.001	3	1
LARGE_INTESTINE	SEPTIN14 →	+0.009	+3.684	<.001	.006	3	1
LARGE_INTESTINE	NPY2R →	+0.005	+4.217	<.001	.001	3	1
LARGE_INTESTINE	PRAMEF20 →	+0.012	+4.437	<.001	.004	3	1
LUNG_NSCLC_LUAD	OR51F2 →	+0.016	+4.662	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

OR5V1 by GSG1L expression — LARGE_INTESTINE

Explore this box plot interactively →