GRM8

Across TCGA patient cohorts, GRM8 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,410 significant associations in total. COAD shows the largest number of these associations.

The most reproducible GRM8-associated proteins across cancer lineages are CXCL14, STAT3_Y705, and WARS1. Each is linked with GRM8 in more than 3 cancer types. Because this analysis shows association rather than direction, both GRM8-to-partner and partner-to-GRM8 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRM8 versus CXCL14 in LSCC, with a Pearson correlation of 0.17.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRM8→partner) and Y-score (partner→GRM8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	CXCL14 →	+1.459	+0.288	<.001	.001	3	4
HNSC	STAT3_Y705 →	-0.363	-0.525	<.001	.006	3	3
COAD	WARS1 →	-0.664	-1.414	.001	.002	3	3
COAD	PRKAR2A →	+0.211	+1.318	<.001	<.001	3	3
COAD	ARHGAP25_S363 →	-0.578	-1.233	.001	.003	3	3
COAD	PALD1 →	+0.393	+1.436	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,410 associations by consensus.

GRM8 vs CXCL14 — LSCC

Explore this scatter interactively →