GRM7-AS1

Across TCGA patient cohorts, GRM7-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,845 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GRM7-AS1-associated GO terms across cancer lineages are Regulation of protein localization to membrane, Bone development, and Cell-matrix adhesion. Each is linked with GRM7-AS1 in more than 14 cancer types. Because this analysis shows association rather than direction, both GRM7-AS1-to-partner and partner-to-GRM7-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to membrane grouped by GRM7-AS1-low versus GRM7-AS1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRM7-AS1→partner) and Y-score (partner→GRM7-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of protein localization to membrane →	+0.050	+0.275	<.001	.004	3	15
ESCA	Bone development →	+0.053	+0.439	<.001	<.001	3	14
STAD	Cell-matrix adhesion →	+0.044	+0.195	<.001	<.001	3	14
STAD	Regulation of intrinsic apoptotic signaling pathway in response to DNA damage →	+0.051	+0.138	<.001	<.001	3	14
ESCA	Negative regulation of cell development →	+0.042	+0.299	<.001	.001	2	15
ESCA	Striated muscle tissue development →	+0.039	+0.310	<.001	<.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,845 associations by consensus.

Regulation of protein localization to membrane by GRM7-AS1 expression — ESCA

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