GRM7-AS1

Across TCGA pan-cancer cohorts, GRM7-AS1 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated GRM7-AS1 data layer.

The strongest signal is observed in pancreatic adenocarcinoma (PAAD), where higher GRM7-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated GRM7-AS1 expression acts as an unfavorable survival marker, although some lineages such as PAAD and READ show a favorable association.

PAAD, LAML, and READ are the cancer types where GRM7-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PAAD	DFS	Median	II,III,IV	0.536	0.352	<.001	91	view →
LAML	DFS	Quartile	All	0.293	0.691	<.001	30	view →
READ	DFS	Tertile	All	0.928	0.457	.012	24	view →
OV	DFS	Median	All	0.499	0.579	.009	22	view →
ACC	OS	Quartile	All	0.601	0.947	.001	22	view →
UCS	DFS	Tertile	IV	0.981	0.514	.013	18	view →
SKCM	OS	Tertile	II,III,IV	0.928	0.788	.004	16	view →
STAD	DFS	Quartile	IV	0.087	0.412	.002	15	view →
LUAD	OS	Tertile	All	0.912	0.798	.004	12	view →
COAD	OS	Tertile	III,IV	0.900	0.501	.038	9	view →
HNSC	OS	Tertile	All	0.476	0.632	.035	9	view →
KIRP	OS	Tertile	III,IV	0.921	0.331	.014	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

GRM7-AS1–PAAD (DFS)

Open the PAAD breakdown →