GRM7-AS1

Across TCGA pan-cancer cohorts, GRM7-AS1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of GRM7-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where GRM7-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GRM7-AS1 is over-expressed in tumor, although a few such as KIRP and LIHC show the opposite, repressed pattern.

THCA, KIRP, and COAD are the cancer types where GRM7-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GRM7-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	II,III,IV	+0.120	.015	5	view →
KIRP	All	All	−0.075	.010	2	view →
COAD	All	All	+0.042	.023	2	view →
LUAD	Female	All	+0.123	.048	1	view →
LIHC	Female	All	−0.071	.044	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

GRM7-AS1–THCA

Open the THCA breakdown →