GRIP1

Across TCGA patient cohorts, GRIP1 protein abundance is significantly associated with the RNA expression of many other genes, with 3,243 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRIP1-associated genes across cancer lineages are FGD2, PRXL2AP1, and ENPP5. Each is linked with GRIP1 in more than 2 cancer types. Because this analysis shows association rather than direction, both GRIP1-to-partner and partner-to-GRIP1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRIP1 versus FGD2 in UCEC, with a Pearson correlation of -0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIP1→partner) and Y-score (partner→GRIP1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	FGD2 →	-0.761	-0.305	.001	.005	3	2
GBM	PRXL2AP1 →	+0.601	+0.420	.001	<.001	3	2
GBM	ENPP5 →	+2.019	+0.546	<.001	<.001	3	2
GBM	PDE1A →	+0.810	+0.379	.005	.004	3	2
UCEC	STAT1 →	-0.827	-0.254	.003	.009	3	2
UCEC	ADGRE2 →	-0.851	-0.305	<.001	.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,243 associations by consensus.

GRIP1 vs FGD2 — UCEC

Explore this scatter interactively →