GRIN2B

RNA expression — cross-omics
Cross-omicsRNA → PROTEIN-MSPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GRIN2B RNA expression is significantly associated with the protein abundance of many other proteins, with 9,823 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRIN2B-associated proteins across cancer lineages are MYO5C, GRIP1_S43, and NCDN. Each is linked with GRIN2B in more than 2 cancer types. Because this analysis shows association rather than direction, both GRIN2B-to-partner and partner-to-GRIN2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRIN2B versus MYO5C in GBM, with a Pearson correlation of -0.35.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIN2B→partner) and Y-score (partner→GRIN2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner proteinX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
GBMMYO5C →-0.707-1.447.001<.00133
GBMGRIP1_S43 →+0.912+1.213<.001.00133
GBMNCDN →+0.628+1.199<.001<.00132
BRCAZNF592_S348 →-0.478-0.083.001<.00132
GBMVPS35 →+0.154+1.308<.001<.00132
COADCADM1 →+0.551+0.325.006.00532
Each partner links to its Q-omics profile. Showing the 6 strongest of 9,823 associations by consensus.

GRIN2B vs MYO5C — GBM

Per-sample scatter of GRIN2B vs MYO5C in GBM (Pearson r = -0.35).

Explore this scatter interactively →

Exploration