GRIN2B

Across TCGA patient cohorts, GRIN2B protein abundance is significantly associated with the RNA expression of many other genes, with 4,124 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRIN2B-associated genes across cancer lineages are SNRPD3, PRODH, and GRK3. Each is linked with GRIN2B in more than 1 cancer types. Because this analysis shows association rather than direction, both GRIN2B-to-partner and partner-to-GRIN2B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRIN2B versus SNRPD3 in GBM, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIN2B→partner) and Y-score (partner→GRIN2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SNRPD3 →	+0.412	+0.534	<.001	<.001	3	1
GBM	PRODH →	+0.799	+0.606	<.001	<.001	3	1
GBM	GRK3 →	+0.459	+0.535	<.001	<.001	3	1
GBM	SEZ6L →	+1.631	+0.555	<.001	<.001	3	1
GBM	SNU13 →	+0.320	+0.449	<.001	.004	3	1
GBM	SOX10 →	+1.096	+0.534	.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,124 associations by consensus.

GRIN2B vs SNRPD3 — GBM

Explore this scatter interactively →