GRIN2B

Across TCGA cell cohorts, GRIN2B RNA expression is significantly associated with the go_rna of many other GO terms, with 965 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible GRIN2B-associated GO terms across cancer lineages are Endosomal transport, Negative regulation of TOR signaling, and Positive regulation of lipid biosynthetic process. Each is linked with GRIN2B in more than 3 cancer types. Because this analysis shows association rather than direction, both GRIN2B-to-partner and partner-to-GRIN2B results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Endosomal transport grouped by GRIN2B-low versus GRIN2B-high in SKIN.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIN2B→partner) and Y-score (partner→GRIN2B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	Endosomal transport →	+0.042	+0.488	<.001	.003	3	4
KIDNEY	Negative regulation of TOR signaling →	+0.031	+0.669	.009	.003	3	4
SKIN	Positive regulation of lipid biosynthetic process →	+0.089	+0.593	<.001	.003	3	4
SKIN	Positive regulation of microtubule nucleation →	+0.165	+0.691	<.001	<.001	3	4
SKIN	GDF15-GFRAL signaling pathway →	+0.653	+0.528	.007	<.001	3	3
SKIN	Response to salt →	+0.112	+0.508	.001	.007	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 965 associations by consensus.

Endosomal transport by GRIN2B expression — SKIN

Explore this box plot interactively →