GRIK3

Across TCGA patient cohorts, GRIK3 protein abundance is significantly associated with the RNA expression of many other genes, with 4,635 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRIK3-associated genes across cancer lineages are TTC12, LINC00276, and GCAT. Each is linked with GRIK3 in more than 1 cancer types. Because this analysis shows association rather than direction, both GRIK3-to-partner and partner-to-GRIK3 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRIK3 versus TTC12 in GBM, with a Pearson correlation of -0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIK3→partner) and Y-score (partner→GRIK3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	TTC12 →	-0.933	-0.666	<.001	<.001	3	2
GBM	LINC00276 →	+0.310	+0.663	<.001	<.001	3	2
OV	GCAT →	+1.081	+1.486	<.001	.008	2	2
OV	CHRNA2 →	-0.055	-1.105	<.001	.005	3	1
OV	SSR2 →	+0.451	+1.152	.001	<.001	3	1
OV	RNASE3 →	-0.580	-1.016	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,635 associations by consensus.

GRIK3 vs TTC12 — GBM

Explore this scatter interactively →