Q-omics provides the consensus-scored LINC00276 profile across patient tissues and cancer cell-line models. LINC00276 expression is associated with patient survival in 15 of 34 cancer types, with the highest sampling consensus in CESC. Among the 18 cancer types available for tumor–normal comparison, LINC00276 is differentially expressed in 5, with the highest sampling consensus in KICH. Additionally, LINC00276 RNA expression shows 7,074 significant protein co-abundance associations, with the highest sampling consensus in GBM. Together, these results highlight CESC, KICH, and GBM as cancer lineages where LINC00276 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for LINC00276 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes LINC00276 survival associations across molecular data types. LINC00276 RNA expression shows survival associations in the most cancer types (15). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible LINC00276 RNA expression–survival associations across cancer types. High LINC00276 expression shows unfavorable associations in CESC, KIRC, GBM, ACC and ESCA, but favorable associations in LUSC. The CESC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p = .002). Together, the overview and detailed table identify CESC as the clearest survival context for LINC00276 RNA expression.
This table summarizes LINC00276 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 5. The strongest signals are observed in KICH for RNA.
This table ranks reproducible tumor–normal expression differences for LINC00276. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. LINC00276 shows lower tumor expression in KICH and COAD and higher tumor expression in THCA, LUAD and LUSC. The KICH box plot shows higher LINC00276 RNA expression in normal versus tumor tissue (log2 FC = −0.032, t-test p < 0.001).
This table shows molecular features associated with LINC00276 in patient tissues and cancer cell lines. In patient samples, LINC00276 shows the broadest associations at the RNA and protein expression levels, with GBM recurring as the lineage with the largest associated feature set.
