GRIK2

Across TCGA patient cohorts, GRIK2 RNA expression is significantly associated with the protein abundance of many other proteins, with 10,624 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRIK2-associated proteins across cancer lineages are DPYSL3, WDR43, and THBS2. Each is linked with GRIK2 in more than 4 cancer types. Because this analysis shows association rather than direction, both GRIK2-to-partner and partner-to-GRIK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRIK2 versus DPYSL3 in COAD, with a Pearson correlation of 0.29.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIK2→partner) and Y-score (partner→GRIK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	DPYSL3 →	+0.538	+0.180	<.001	.001	3	5
BRCA	WDR43 →	-0.326	-0.394	.001	<.001	3	4
COAD	THBS2 →	+0.952	+0.134	<.001	.009	3	4
COAD	TIMP2 →	+0.524	+0.287	<.001	<.001	3	4
LSCC	VCL_S346 →	+0.605	+0.771	<.001	<.001	3	4
LSCC	VCL_S795 →	+0.617	+0.764	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,624 associations by consensus.

GRIK2 vs DPYSL3 — COAD

Explore this scatter interactively →