GRIK2

Across TCGA patient cohorts, GRIK2 protein abundance is significantly associated with the RNA expression of many other genes, with 2,636 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRIK2-associated genes across cancer lineages are LGALS1, POLR2F, and SOX10. Each is linked with GRIK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GRIK2-to-partner and partner-to-GRIK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRIK2 versus LGALS1 in GBM, with a Pearson correlation of -0.32.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRIK2→partner) and Y-score (partner→GRIK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	LGALS1 →	-0.467	-0.375	.006	.001	3	1
GBM	POLR2F →	+0.538	+0.417	<.001	.002	3	1
GBM	SOX10 →	+1.314	+0.443	.001	.003	3	1
GBM	SEPTIN3 →	+1.071	+0.546	.004	.002	3	1
GBM	KDELR3 →	-0.559	-0.669	<.001	<.001	3	1
GBM	DMC1 →	-0.133	-0.480	.003	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,636 associations by consensus.

GRIK2 vs LGALS1 — GBM

Explore this scatter interactively →