GRAP2

Across TCGA cell cohorts, GRAP2 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GRAP2-associated genes across cancer lineages are ZNF831, TFDP3, and VAX1. Each is linked with GRAP2 in more than 1 cancer types. Because this analysis shows association rather than direction, both GRAP2-to-partner and partner-to-GRAP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF831 grouped by GRAP2-low versus GRAP2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRAP2→partner) and Y-score (partner→GRAP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ZNF831 →	+0.013	+3.688	<.001	.002	3	1
LARGE_INTESTINE	TFDP3 →	+0.020	+3.196	.001	.007	3	1
LARGE_INTESTINE	VAX1 →	+1.108	+3.519	<.001	.007	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

ZNF831 by GRAP2 expression — LARGE_INTESTINE

Explore this box plot interactively →