GRAMD1B

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GRAMD1B protein abundance is significantly associated with the RNA expression of many other genes, with 5,085 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GRAMD1B-associated genes across cancer lineages are TNFRSF10B, PGM2, and TLR4. Each is linked with GRAMD1B in more than 1 cancer types. Because this analysis shows association rather than direction, both GRAMD1B-to-partner and partner-to-GRAMD1B results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GRAMD1B versus TNFRSF10B in LUAD, with a Pearson correlation of 0.56.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GRAMD1B→partner) and Y-score (partner→GRAMD1B) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUADTNFRSF10B →+0.884+1.272<.001.00132
LUADPGM2 →+0.673+1.634.002.00332
GBMTLR4 →+0.572+0.311<.001<.00132
GBMNT5C1A →+0.661+0.328<.001<.00132
GBMASPM →-0.659-0.275.004.00332
UCECDDB2 →+0.855+0.955.003.00932
Each partner links to its Q-omics profile. Showing the 6 strongest of 5,085 associations by consensus.

GRAMD1B vs TNFRSF10B — LUAD

Per-sample scatter of GRAMD1B vs TNFRSF10B in LUAD (Pearson r = 0.56).

Explore this scatter interactively →

Exploration