Across TCGA cell cohorts, GPX6 RNA expression is significantly associated with the RNA expression of many other genes, with 519 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPX6-associated genes across cancer lineages are OR2A25, FAM47B, and METTL21C. Each is linked with GPX6 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPX6-to-partner and partner-to-GPX6 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPX6→partner) and Y-score (partner→GPX6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	OR2A25 →	+0.087	+0.002	<.001	.002	3	3
PANCREAS	FAM47B →	+0.014	+0.004	<.001	<.001	3	3
LARGE_INTESTINE	METTL21C →	+0.083	+0.376	.001	<.001	3	3
LARGE_INTESTINE	LY6L →	+0.064	+0.798	.006	<.001	3	2
STOMACH	SCYGR4 →	+0.102	+0.040	<.001	.008	3	2
BLOOD_Lymphoma	PRAMEF20 →	+0.205	+0.009	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 519 associations by consensus.

Exploration

GPX6 survival (RNA) · tumor vs normal (RNA) · all GPX6 data types