GPX3

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, GPX3 mutation is significantly associated with the RNA expression of many other genes, with 890 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPX3-associated genes across cancer lineages are IL9, HPRT1P1, and DAZ2. Each is linked with GPX3 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPX3-to-partner and partner-to-GPX3 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPX3→partner) and Y-score (partner→GPX3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLCAIL9 →+0.163+5.251.001.00633
READHPRT1P1 →+0.127+5.925<.001.00232
BLCADAZ2 →+0.654+6.018<.001.00232
UCECRNA5SP418 →+0.728+2.126<.001.00732
UCECRNA5SP415 →+0.554+2.751<.001<.00132
UCECOSTF1P1 →+0.211+3.204.001<.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 890 associations by consensus.

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