Q-omics provides the consensus-scored HPRT1P1 profile across patient tissues and cancer cell-line models. HPRT1P1 expression is associated with patient survival in 12 of 34 cancer types, with the highest sampling consensus in LIHC. Additionally, HPRT1P1 RNA expression shows 7,385 significant gene co-expression associations, with the highest sampling consensus in TGCT. Together, these results highlight LIHC, and TGCT as cancer lineages where HPRT1P1 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.

Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.

Premium analyses for HPRT1P1 — synthetic lethality, tumor antigen, and pembrolizumab response.

View premium →

Survival associations

This table summarizes HPRT1P1 survival associations across molecular data types. HPRT1P1 RNA expression shows survival associations in the most cancer types (12). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.

HPRT1P1 data type	Survival analysis	Lineage consensus	Lineage of highest sampling consensus
RNA	Kaplan–Meier	12	LIHC (75)	view →

This table ranks reproducible HPRT1P1 RNA expression–survival associations across cancer types. High HPRT1P1 expression shows unfavorable associations in LIHC, THYM, CESC, MESO and ESCA, but favorable associations in LUAD. The LIHC Kaplan–Meier curve shows clear separation, with the high-expression group declining faster, consistent with the unfavorable association (log-rank p < 0.001). Together, the overview and detailed table identify LIHC as the clearest survival context for HPRT1P1 RNA expression.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LIHC	DFS	Tertile	II,III,IV	0.108	0.425	<.001	75	view →
THYM	OS	Tertile	All	0.854	0.980	.001	72	view →
CESC	OS	Tertile	IV	0.121	0.591	.029	54	view →
MESO	OS	Tertile	III,IV	0.212	0.586	.013	54	view →
LUAD	DFS	Tertile	II,III,IV	1.000	0.412	.042	12	view →
ESCA	DFS	Tertile	II,III,IV	0.131	0.776	.043	10	view →

Pink = unfavorable, green = favorable. all 12 lineages →

HPRT1P1-LIHC (DFS)

Kaplan–Meier survival curve for HPRT1P1 RNA expression in LIHC: high vs low expression groups.

Explore this curve interactively →

Cross-omics associations

This table shows molecular features associated with HPRT1P1 in patient tissues and cancer cell lines. In patient samples, HPRT1P1 shows the broadest associations at the RNA and protein expression levels, with TGCT recurring as the lineage with the largest associated feature set.

Associated data type	Strength (# associated data)	Lineage of highest associated data
▼RNA
RNA	7,385	TGCT (4259)	view →
Function (RNA)	6,356	STAD (5747)	view →