HPRT1P1

Across TCGA patient cohorts, HPRT1P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,356 significant associations in total. STAD shows the largest number of these associations.

The most reproducible HPRT1P1-associated GO terms across cancer lineages are Regulation of double-strand break repair, DNA conformation change, and Regulation of microtubule-based process. Each is linked with HPRT1P1 in more than 12 cancer types. Because this analysis shows association rather than direction, both HPRT1P1-to-partner and partner-to-HPRT1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of double-strand break repair grouped by HPRT1P1-low versus HPRT1P1-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (HPRT1P1→partner) and Y-score (partner→HPRT1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of double-strand break repair →	+0.079	+0.183	<.001	<.001	3	13
STAD	DNA conformation change →	+0.085	+0.188	<.001	<.001	3	13
STAD	Regulation of microtubule-based process →	+0.061	+0.173	<.001	<.001	3	12
STAD	Positive regulation of translation →	+0.086	+0.179	<.001	<.001	3	12
STAD	DNA-templated DNA replication →	+0.086	+0.158	<.001	<.001	3	12
STAD	Protein-DNA complex assembly →	+0.074	+0.215	<.001	<.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,356 associations by consensus.

Regulation of double-strand break repair by HPRT1P1 expression — STAD

Explore this box plot interactively →