GPSM2

Across TCGA patient cohorts, GPSM2 RNA expression is significantly associated with the protein abundance of many other proteins, with 18,773 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPSM2-associated proteins across cancer lineages are SMC2, SMC4, and TOP2A_S1106. Each is linked with GPSM2 in more than 7 cancer types. Because this analysis shows association rather than direction, both GPSM2-to-partner and partner-to-GPSM2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPSM2 versus SMC2 in OV, with a Pearson correlation of 0.68.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPSM2→partner) and Y-score (partner→GPSM2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	SMC2 →	+0.583	+0.761	<.001	<.001	3	8
OV	SMC4 →	+0.590	+0.752	<.001	<.001	3	8
LUAD	TOP2A_S1106 →	+0.945	+0.543	<.001	<.001	3	8
BRCA	GPSM2_S408 →	+0.532	+0.955	<.001	<.001	3	8
OV	POLD1 →	+0.395	+0.679	<.001	<.001	3	7
BRCA	PUS7 →	+0.466	+0.620	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 18,773 associations by consensus.

GPSM2 vs SMC2 — OV

Explore this scatter interactively →