GPRC5C

Across TCGA patient cohorts, GPRC5C protein abundance is significantly associated with the RNA expression of many other genes, with 7,611 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GPRC5C-associated genes across cancer lineages are TOX3, DOCK11, and SPINT1-AS1. Each is linked with GPRC5C in more than 4 cancer types. Because this analysis shows association rather than direction, both GPRC5C-to-partner and partner-to-GPRC5C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPRC5C versus TOX3 in BRCA, with a Pearson correlation of 0.36.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPRC5C→partner) and Y-score (partner→GPRC5C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	TOX3 →	+1.223	+0.771	.001	.004	3	4
GBM	DOCK11 →	-0.910	-1.604	<.001	.001	3	4
OV	SPINT1-AS1 →	+0.837	+1.102	<.001	.001	3	4
OV	CYB561 →	+0.898	+1.476	.002	<.001	2	5
BRCA	ESRP2 →	+0.794	+0.792	<.001	<.001	3	4
LUAD	ITK →	-0.941	-0.957	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,611 associations by consensus.

GPRC5C vs TOX3 — BRCA

Explore this scatter interactively →