GPR83

Across TCGA cell cohorts, GPR83 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,990 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPR83-associated GO terms across cancer lineages are Regulation of transcription elongation by RNA polymerase II, Subtelomeric heterochromatin formation, and Regulation of centrosome cycle. Each is linked with GPR83 in more than 8 cancer types. Because this analysis shows association rather than direction, both GPR83-to-partner and partner-to-GPR83 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of transcription elongation by RNA polymerase II grouped by GPR83-low versus GPR83-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR83→partner) and Y-score (partner→GPR83) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of transcription elongation by RNA polymerase II →	+0.069	+0.109	<.001	.009	3	9
STOMACH	Subtelomeric heterochromatin formation →	+0.093	+0.229	.001	.003	2	9
LUNG_SCLC	Regulation of centrosome cycle →	+0.108	+0.507	<.001	.001	3	8
SOFT_TISSUE	Regulation of RNA splicing →	+0.067	+0.182	<.001	.003	3	8
LARGE_INTESTINE	Co-transcriptional RNA 3'-end processing, cleavage and polyadenylation pathway →	+0.104	+0.233	<.001	.002	3	7
LARGE_INTESTINE	Regulation of DNA biosynthetic process →	+0.064	+0.284	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,990 associations by consensus.

Regulation of transcription elongation by RNA polymerase II by GPR83 expression — SOFT_TISSUE

Explore this box plot interactively →