GPR37L1

Across TCGA cell cohorts, GPR37L1 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPR37L1-associated genes across cancer lineages are MAS1, OR4N4, and TCP11X1. Each is linked with GPR37L1 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR37L1-to-partner and partner-to-GPR37L1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, MAS1 grouped by GPR37L1-low versus GPR37L1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR37L1→partner) and Y-score (partner→GPR37L1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	MAS1 →	+0.006	+6.022	<.001	.001	3	1
LARGE_INTESTINE	OR4N4 →	+0.029	+4.977	<.001	.007	3	1
LARGE_INTESTINE	TCP11X1 →	+0.006	+4.977	<.001	.007	3	1
BLOOD_Leukemia	MMP27 →	+0.015	+4.384	<.001	.006	3	1
BLOOD_Leukemia	C16orf92 →	+0.152	+4.037	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

MAS1 by GPR37L1 expression — LARGE_INTESTINE

Explore this box plot interactively →