Across TCGA cell cohorts, GPR20 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible GPR20-associated genes across cancer lineages are CFAP47, BPIFB6, and OR52A1. Each is linked with GPR20 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR20-to-partner and partner-to-GPR20 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR20→partner) and Y-score (partner→GPR20) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	CFAP47 →	+0.366	+3.453	<.001	.009	3	1
LARGE_INTESTINE	BPIFB6 →	+0.016	+4.022	<.001	.006	3	1
LARGE_INTESTINE	OR52A1 →	+0.008	+3.347	<.001	.005	3	1
LARGE_INTESTINE	PNMA8C →	+0.007	+3.345	<.001	.007	3	1
LARGE_INTESTINE	WDR87 →	+0.017	+3.453	.003	.009	2	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

Exploration

GPR20 survival (RNA) · tumor vs normal (RNA) · all GPR20 data types