GPR176-DT

Across TCGA patient cohorts, GPR176-DT RNA expression is significantly associated with the protein abundance of many other proteins, with 8,780 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPR176-DT-associated proteins across cancer lineages are SAP130, KIF20A_S532, and MCM2_S139. Each is linked with GPR176-DT in more than 3 cancer types. Because this analysis shows association rather than direction, both GPR176-DT-to-partner and partner-to-GPR176-DT results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR176-DT versus SAP130 in GBM, with a Pearson correlation of 0.12.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR176-DT→partner) and Y-score (partner→GPR176-DT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	SAP130 →	+0.231	+0.130	.008	.002	2	4
BRCA	KIF20A_S532 →	+0.612	+0.041	<.001	<.001	3	3
BRCA	MCM2_S139 →	+0.625	+0.056	<.001	<.001	3	3
LSCC	BRD2 →	+0.229	+0.091	<.001	<.001	3	3
LSCC	TDRKH →	+0.352	+0.089	.008	.008	3	3
PDAC	TPX2_S486 →	+1.443	+0.160	.003	.008	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 8,780 associations by consensus.

GPR176-DT vs SAP130 — GBM

Explore this scatter interactively →