GPR17

Across TCGA cell cohorts, GPR17 RNA expression is significantly associated with the go_rna of many other GO terms, with 2,431 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPR17-associated GO terms across cancer lineages are Microtubule cytoskeleton organization involved in mitosis, Platelet activation, and Establishment of RNA localization. Each is linked with GPR17 in more than 7 cancer types. Because this analysis shows association rather than direction, both GPR17-to-partner and partner-to-GPR17 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule cytoskeleton organization involved in mitosis grouped by GPR17-low versus GPR17-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR17→partner) and Y-score (partner→GPR17) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Microtubule cytoskeleton organization involved in mitosis →	+0.089	+0.713	.003	.005	3	7
LIVER	Platelet activation →	+0.093	+0.492	.008	.005	2	8
BLOOD_Leukemia	Establishment of RNA localization →	+0.049	+0.153	<.001	.001	3	7
BONE	Regulation of hippo signaling →	+0.080	+0.938	<.001	<.001	2	7
KIDNEY	Establishment of protein localization to plasma membrane →	+0.060	+0.389	.002	.007	3	6
OESOPHAGUS	Establishment or maintenance of cell polarity →	+0.055	+0.283	.006	.002	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,431 associations by consensus.

Microtubule cytoskeleton organization involved in mitosis by GPR17 expression — BONE

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