GPR161

Across TCGA patient cohorts, GPR161 mutation is significantly associated with the RNA expression of many other genes, with 2,178 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR161-associated genes across cancer lineages are RN7SL134P, LINC01939, and OR12D1. Each is linked with GPR161 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPR161-to-partner and partner-to-GPR161 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL134P grouped by GPR161-low versus GPR161-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR161→partner) and Y-score (partner→GPR161) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RN7SL134P →	+0.116	+2.236	<.001	.001	3	3
READ	LINC01939 →	+0.076	+4.925	<.001	.004	3	2
READ	OR12D1 →	+0.081	+5.257	<.001	.002	3	2
COAD	TRAV10 →	+0.489	+3.544	.004	.005	3	2
COAD	TRAJ52 →	+0.608	+3.169	.001	.004	3	2
COAD	DYNLT3P2 →	+0.358	+3.405	.008	.007	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,178 associations by consensus.

RN7SL134P by GPR161 expression — UCEC

Explore this box plot interactively →