GPR161

Across TCGA cell cohorts, GPR161 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,888 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible GPR161-associated GO terms across cancer lineages are Microtubule cytoskeleton organization involved in mitosis, Cytokinesis, and Establishment of spindle orientation. Each is linked with GPR161 in more than 13 cancer types. Because this analysis shows association rather than direction, both GPR161-to-partner and partner-to-GPR161 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Microtubule cytoskeleton organization involved in mitosis grouped by GPR161-low versus GPR161-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR161→partner) and Y-score (partner→GPR161) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Microtubule cytoskeleton organization involved in mitosis →	+0.084	+1.422	<.001	.001	3	14
OVARY	Cytokinesis →	+0.064	+0.967	<.001	.001	3	13
STOMACH	Establishment of spindle orientation →	+0.119	+2.030	<.001	<.001	3	13
BREAST	Cell division →	+0.079	+1.494	<.001	<.001	3	12
BONE	Negative regulation of transcription initiation by RNA polymerase II →	+0.097	+0.983	.001	<.001	3	12
OVARY	Cytoskeleton-dependent cytokinesis →	+0.062	+0.967	<.001	.001	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,888 associations by consensus.

Microtubule cytoskeleton organization involved in mitosis by GPR161 expression — BREAST

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