GPR158-AS1

Across TCGA patient cohorts, GPR158-AS1 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,718 significant associations in total. STAD shows the largest number of these associations.

The most reproducible GPR158-AS1-associated GO terms across cancer lineages are Aerobic respiration, Oxidative phosphorylation, and Protein targeting to mitochondrion. Each is linked with GPR158-AS1 in more than 12 cancer types. Because this analysis shows association rather than direction, both GPR158-AS1-to-partner and partner-to-GPR158-AS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Aerobic respiration grouped by GPR158-AS1-low versus GPR158-AS1-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR158-AS1→partner) and Y-score (partner→GPR158-AS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Aerobic respiration →	+0.071	+0.088	<.001	.003	3	13
STAD	Oxidative phosphorylation →	+0.061	+0.083	<.001	<.001	3	12
ESCA	Protein targeting to mitochondrion →	+0.066	+0.099	<.001	.003	3	12
STAD	Proton motive force-driven ATP synthesis →	+0.065	+0.086	<.001	<.001	3	11
ESCA	Mitochondrial electron transport, NADH to ubiquinone →	+0.075	+0.116	<.001	.002	3	11
STAD	Protein localization to mitochondrion →	+0.049	+0.086	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,718 associations by consensus.

Aerobic respiration by GPR158-AS1 expression — ESCA

Explore this box plot interactively →