GPR158-AS1

Across TCGA pan-cancer cohorts, GPR158-AS1 RNA differs between tumor and matched normal tissue in 3 of 18 cancer types tested, making tumor–normal expression one of GPR158-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where GPR158-AS1 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types GPR158-AS1 is over-expressed in tumor.

UCEC, BRCA, and KIRC are the cancer types where GPR158-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in GPR158-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	IV	+0.065	.049	2	view →
BRCA	All	II,III,IV	+0.009	.039	2	view →
KIRC	Male	II,III,IV	+0.003	.042	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 3 strongest of 3 lineages.

GPR158-AS1–UCEC

Open the UCEC breakdown →