GPR152

Across TCGA cell cohorts, GPR152 mutation is significantly associated with the RNA expression of many other genes, with 35 significant associations in total. LUNG_NSCLC_LUAD shows the largest number of these associations.

The most reproducible GPR152-associated genes across cancer lineages are SERPINA7, HNRNPCL4, and FAM205C. Each is linked with GPR152 in more than 1 cancer types. Because this analysis shows association rather than direction, both GPR152-to-partner and partner-to-GPR152 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SERPINA7 grouped by GPR152-low versus GPR152-high in SOFT_TISSUE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR152→partner) and Y-score (partner→GPR152) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	SERPINA7 →	+0.012	+4.930	<.001	.008	3	1
LARGE_INTESTINE	HNRNPCL4 →	+0.060	+3.793	<.001	.007	3	1
LARGE_INTESTINE	FAM205C →	+0.012	+4.437	<.001	.004	3	1
LARGE_INTESTINE	GSG1L2 →	+0.016	+4.437	<.001	.004	3	1
LARGE_INTESTINE	KIR3DL3 →	+0.004	+4.437	<.001	.004	3	1
BLOOD_Leukemia	SLC28A2 →	+0.046	+3.744	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 35 associations by consensus.

SERPINA7 by GPR152 expression — SOFT_TISSUE

Explore this box plot interactively →