GPR149

Across TCGA patient cohorts, GPR149 RNA expression is significantly associated with the protein abundance of many other proteins, with 7,490 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPR149-associated proteins across cancer lineages are EPB41L1_T489, AKAP1_S445, and ARHGEF26_S222. Each is linked with GPR149 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPR149-to-partner and partner-to-GPR149 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR149 versus EPB41L1_T489 in GBM, with a Pearson correlation of 0.32.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR149→partner) and Y-score (partner→GPR149) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
GBM	EPB41L1_T489 →	+1.221	+0.267	<.001	.007	3	3
LSCC	AKAP1_S445 →	+0.646	+0.683	.004	.005	3	3
LSCC	ARHGEF26_S222 →	+1.055	+0.788	<.001	.002	3	3
GBM	SGIP1_S550 →	+0.920	+0.184	<.001	.001	3	3
LSCC	MAP1B_T1282 →	+1.157	+0.514	<.001	.009	3	3
GBM	RIPK1 →	-0.283	-0.227	<.001	.004	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,490 associations by consensus.

GPR149 vs EPB41L1_T489 — GBM

Explore this scatter interactively →