GPR142

Across TCGA patient cohorts, GPR142 RNA expression is significantly associated with the go_rna of many other GO terms, with 7,132 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible GPR142-associated GO terms across cancer lineages are Regulation of actin filament organization, Phosphatidylinositol metabolic process, and Glycerophospholipid metabolic process. Each is linked with GPR142 in more than 26 cancer types. Because this analysis shows association rather than direction, both GPR142-to-partner and partner-to-GPR142 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of actin filament organization grouped by GPR142-low versus GPR142-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR142→partner) and Y-score (partner→GPR142) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of actin filament organization →	+0.067	+0.434	<.001	<.001	3	27
DLBC	Phosphatidylinositol metabolic process →	+0.060	+0.558	<.001	<.001	3	27
ESCA	Glycerophospholipid metabolic process →	+0.049	+0.642	<.001	<.001	3	27
STAD	Phosphatidylinositol biosynthetic process →	+0.053	+0.362	<.001	<.001	3	27
STAD	Maintenance of protein location →	+0.067	+0.357	<.001	<.001	3	26
STAD	Regulation of small GTPase mediated signal transduction →	+0.067	+0.438	<.001	<.001	3	26

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,132 associations by consensus.

Regulation of actin filament organization by GPR142 expression — STAD

Explore this box plot interactively →