GPR142

Across TCGA patient cohorts, GPR142 mutation is significantly associated with the total protein of many other genes, with 40 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR142-associated genes across cancer lineages are JNK2, Caspase-7-cleavedD198, and INPP4B. Each is linked with GPR142 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPR142-to-partner and partner-to-GPR142 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, JNK2 grouped by GPR142-low versus GPR142-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR142→partner) and Y-score (partner→GPR142) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	JNK2 →	+0.200	+1.584	.010	.036	3	3
UCEC	Caspase-7-cleavedD198 →	+0.911	+2.135	<.001	.010	3	3
UCEC	INPP4B →	-0.318	-3.584	.012	.002	3	2
SKCM	ACVRL1 →	-0.155	-2.987	.020	.035	3	2
UCEC	Rictor_pT1135 →	-0.112	-3.459	.005	.005	3	2
UCEC	TFRC →	+0.710	+2.700	<.001	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 40 associations by consensus.

JNK2 by GPR142 expression — UCEC

Explore this box plot interactively →