GPR137C

Across TCGA patient cohorts, GPR137C RNA expression is significantly associated with the protein abundance of many other proteins, with 17,561 significant associations in total. GBM shows the largest number of these associations.

The most reproducible GPR137C-associated proteins across cancer lineages are DBN1, FADS2, and SOX4. Each is linked with GPR137C in more than 5 cancer types. Because this analysis shows association rather than direction, both GPR137C-to-partner and partner-to-GPR137C results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR137C versus DBN1 in LSCC, with a Pearson correlation of 0.36.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR137C→partner) and Y-score (partner→GPR137C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DBN1 →	+0.394	+0.522	<.001	.001	3	6
UCEC	FADS2 →	+0.870	+0.985	<.001	<.001	3	6
HNSC	SOX4 →	+1.573	+0.904	.001	.002	3	5
HNSC	SOX4_S354 →	+1.220	+0.832	<.001	.001	3	5
GBM	RSF1 →	+0.320	+0.667	<.001	<.001	3	5
PDAC	SMAD4 →	+0.291	+0.382	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,561 associations by consensus.

GPR137C vs DBN1 — LSCC

Explore this scatter interactively →