GPR137C

Across TCGA cell cohorts, GPR137C RNA expression is significantly associated with the go_rna of many other GO terms, with 4,931 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible GPR137C-associated GO terms across cancer lineages are Regulation of sister chromatid segregation, Regulation of chromosome segregation, and Regulation of metaphase/anaphase transition of cell cycle. Each is linked with GPR137C in more than 14 cancer types. Because this analysis shows association rather than direction, both GPR137C-to-partner and partner-to-GPR137C results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of sister chromatid segregation grouped by GPR137C-low versus GPR137C-high in BREAST.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR137C→partner) and Y-score (partner→GPR137C) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BREAST	Regulation of sister chromatid segregation →	+0.097	+1.176	.004	<.001	3	15
STOMACH	Regulation of chromosome segregation →	+0.111	+0.912	<.001	.004	3	15
BLOOD_Lymphoma	Regulation of metaphase/anaphase transition of cell cycle →	+0.114	+0.606	<.001	<.001	3	15
UPPER_AERODIGESTIVE_TRACT	Regulation of chromosome organization →	+0.072	+0.585	.003	.004	3	15
BLOOD_Lymphoma	Regulation of mitotic metaphase/anaphase transition →	+0.115	+0.612	<.001	<.001	3	14
BREAST	Cell division →	+0.078	+1.069	.006	.005	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,931 associations by consensus.

Regulation of sister chromatid segregation by GPR137C expression — BREAST

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