GPR108

Across TCGA patient cohorts, GPR108 protein abundance is significantly associated with the RNA expression of many other genes, with 11,985 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible GPR108-associated genes across cancer lineages are MCM7, NAB2, and NT5C. Each is linked with GPR108 in more than 3 cancer types. Because this analysis shows association rather than direction, both GPR108-to-partner and partner-to-GPR108 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, GPR108 versus MCM7 in UCEC, with a Pearson correlation of -0.34.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR108→partner) and Y-score (partner→GPR108) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	MCM7 →	-1.141	-0.528	.001	.002	3	4
LSCC	NAB2 →	-0.599	-0.434	<.001	<.001	3	4
UCEC	NT5C →	-0.971	-0.330	.008	.008	3	4
UCEC	KIF15 →	-1.323	-0.646	<.001	<.001	3	4
UCEC	RCOR2 →	-1.251	-0.575	<.001	<.001	3	4
PDAC	BHLHA15 →	+0.969	+0.341	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,985 associations by consensus.

GPR108 vs MCM7 — UCEC

Explore this scatter interactively →