GPR107

Across TCGA patient cohorts, GPR107 mutation is significantly associated with the RNA expression of many other genes, with 1,728 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible GPR107-associated genes across cancer lineages are SNORD116-10, IGHVII-33-1, and USP17L3. Each is linked with GPR107 in more than 2 cancer types. Because this analysis shows association rather than direction, both GPR107-to-partner and partner-to-GPR107 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNORD116-10 grouped by GPR107-low versus GPR107-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (GPR107→partner) and Y-score (partner→GPR107) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	SNORD116-10 →	+0.519	+6.624	<.001	.001	3	3
CESC	IGHVII-33-1 →	+0.133	+3.922	.001	.003	3	2
LUSC	USP17L3 →	+0.039	+7.924	<.001	.008	3	2
LUAD	RNU6-497P →	+0.403	+5.481	<.001	.005	3	2
LUAD	MTND6P16 →	+0.101	+5.798	<.001	.003	3	2
LUSC	RNU6-491P →	+0.294	+7.924	<.001	.008	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,728 associations by consensus.

SNORD116-10 by GPR107 expression — SKCM

Explore this box plot interactively →